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sck2 serine/threonine protein kinase S6K family Sck2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541867, updated on 18-Sep-2024

Summary

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Official Symbol
sck2
Official Full Name
serine/threonine protein kinase S6K family Sck2
Primary source
PomBase:SPAC22E12.14c
Locus tag
SPOM_SPAC22E12.14C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sck2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (5045616..5049012, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein rlp24 Neighboring gene tRNA-Arg Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Golgi-specific 1-phosphatidylinositol 4-kinase, type III-beta Pik1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity. Chen BR, et al. Exp Gerontol, 2009 Aug. PMID 19409973, Free PMC Article
  2. S. pombe sck2+, a second homologue of S. cerevisiae SCH9 in fission yeast, encodes a putative protein kinase closely related to PKA in function. Fujita M, et al. Curr Genet, 1998 Apr. PMID 9560431
  3. Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling. Becker M, et al. Nucleic Acids Res, 2012 Dec. PMID 23074192, Free PMC Article
  4. A metabolic strategy to enhance long-term survival by Phx1 through stationary phase-specific pyruvate decarboxylases in fission yeast. Kim JY, et al. Aging (Albany NY), 2014 Jul. PMID 25102102, Free PMC Article
  5. Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway. Zuin A, et al. EMBO J, 2010 Mar 3. PMID 20075862, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in TORC1 signaling IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular signal transduction IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of conjugation with cellular fusion IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nuclear envelope HDA PubMed 

General protein information

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Preferred Names
serine/threonine protein kinase S6K family Sck2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5045616..5049012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020269.3 → NP_594840.1  serine/threonine protein kinase S6K family Sck2 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10364
    Conserved Domains (2) summary
    smart00220
    Location:266 → 527
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:272 → 595
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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