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vma1 V-type ATPase V1 domain-containing subunit A [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541660, updated on 18-Sep-2024

Summary

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Official Symbol
vma1
Official Full Name
V-type ATPase V1 domain-containing subunit A
Primary source
PomBase:SPAC343.05
Locus tag
SPOM_SPAC343.05
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See vma1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (1647218..1649410)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phospholipid scramblase Neighboring gene mitochondrial 37S ribosomal protein bS6m Neighboring gene RNA-binding protein Mug28, implicated in mRNA processing

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A simple and specific procedure to permeabilize the plasma membrane of Schizosaccharomyces pombe. Chardwiriyapreecha S, et al. Biosci Biotechnol Biochem, 2009 Sep. PMID 19734666
  2. Characterization of Schizosaccharomyces pombe mutants defective in vacuolar acidification and protein sorting. Iwaki T, et al. Mol Genet Genomics, 2004 Mar. PMID 14735354
  3. btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis. Gachet Y, et al. J Cell Sci, 2005 Dec 1. PMID 16291725
  4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding ISM
Inferred from Sequence Model
more info
  
enables ATP hydrolysis activity IC
Inferred by Curator
more info
  
enables proton-transporting ATPase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ATP metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular arginine homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular histidine homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular lysine homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in endomembrane system IEA
Inferred from Electronic Annotation
more info
  
is_active_in fungal-type vacuole membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of vacuolar proton-transporting V-type ATPase, V1 domain ISO
Inferred from Sequence Orthology
more info
 PubMed 

General protein information

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Preferred Names
V-type ATPase V1 domain-containing subunit A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1647218..1649410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018858.3 → NP_593425.1  V-type ATPase V1 domain-containing subunit A [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593425.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P31406
    Conserved Domains (4) summary
    cd01134
    Location:92 → 465
    V_A-ATPase_A; V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi ...
    TIGR01042
    Location:24 → 611
    V-ATPase_V1_A; V-type (H+)-ATPase V1, A subunit
    pfam00306
    Location:483 → 619
    ATP-synt_ab_C; ATP synthase alpha/beta chain, C terminal domain
    pfam02874
    Location:28 → 90
    ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain
Nucleotide Protein
Heading Accession and Version

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