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ppa3 protein phosphatase type 2A [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541444, updated on 18-Sep-2024

Summary

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Official Symbol
ppa3
Official Full Name
protein phosphatase type 2A
Primary source
PomBase:SPAC22H10.04
Locus tag
SPOM_SPAC22H10.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ppg1
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Genomic context

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See ppa3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2377057..2378678)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene karyopherin/importin beta family nuclear import signal receptor Kap14 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cleavage and polyadenylation specificity factor complex subunit Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain. Willet AH, et al. Mol Biol Cell, 2024 Aug 1. PMID 38865179, Free PMC Article
  2. SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast. Singh NS, et al. Curr Biol, 2011 Dec 6. PMID 22119525, Free PMC Article
  3. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
  4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
  5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables phosphoprotein phosphatase activity EXP
Inferred from Experiment
more info
 PubMed 
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in asymmetric protein localization to old mitotic spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in asymmetric protein localization to old mitotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of FAR/SIN/STRIPAK complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase type 2A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2377057..2378678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019171.3 → NP_593740.1  protein phosphatase type 2A [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593740.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10298
    Conserved Domains (2) summary
    smart00156
    Location:17 → 288
    PP2Ac; Protein phosphatase 2A homologues, catalytic domain
    cd07415
    Location:3 → 288
    MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials