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ubc7 ubiquitin-conjugating enzyme Ubc7 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541252, updated on 14-Nov-2024

Summary

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Official Symbol
ubc7
Official Full Name
ubiquitin-conjugating enzyme Ubc7
Primary source
PomBase:SPBP16F5.04
Locus tag
SPOM_SPBP16F5.04
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ubcP3
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Genomic context

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See ubc7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (1905688..1907025)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene SAGA complex, phosphatidylinositol pseudokinase subunit Tra1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Yar1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7. Hann ZS, et al. Acta Crystallogr F Struct Biol Commun, 2019 Aug 1. PMID 31397327, Free PMC Article
  2. Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast. Hughes BT, et al. J Biol Chem, 2009 Jul 31. PMID 19520858, Free PMC Article
  3. A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis. Le TK, et al. J Cell Sci, 2023 Oct 1. PMID 37694715
  4. A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis. Osaka F, et al. Mol Cell Biol, 1997 Jun. PMID 9154838, Free PMC Article
  5. S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Lv Z, et al. Mol Cell, 2017 Feb 16. PMID 28162934, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin conjugating enzyme activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin conjugating enzyme activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ERAD pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in inner nuclear membrane-associated protein degradation pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
ubiquitin-conjugating enzyme Ubc7

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1905688..1907025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021678.3 → NP_595778.1  ubiquitin-conjugating enzyme Ubc7 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O00102, Q9HDP3
    Conserved Domains (2) summary
    COG5078
    Location:1 → 164
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    pfam00179
    Location:9 → 160
    UQ_con; Ubiquitin-conjugating enzyme
Nucleotide Protein
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