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erg9 squalene synthase Erg9 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541110, updated on 14-Nov-2024

Summary

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Official Symbol
erg9
Official Full Name
squalene synthase Erg9
Primary source
PomBase:SPBC646.05c
Locus tag
SPOM_SPBC646.05C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See erg9 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (931002..932472, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene protein Cwf11 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutamyl-tRNA amidotransferase alpha subunit Neighboring gene mRNA cleavage and polyadenylation specificity factor poly(A) polymerase Pla1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glucan endo-1,3-alpha-glucosidase Agn2 Neighboring gene enoyl reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation. Robinson GW, et al. Mol Cell Biol, 1993 May. PMID 8474436, Free PMC Article
  2. Repression of ergosterol level during oxidative stress by fission yeast F-box protein Pof14 independently of SCF. Tafforeau L, et al. EMBO J, 2006 Oct 4. PMID 17016471, Free PMC Article
  3. Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. Das J, et al. Sci Signal, 2013 May 21. PMID 23695164, Free PMC Article
  4. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables squalene synthase [NAD(P)H] activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ergosterol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in farnesyl diphosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in isoprenoid biosynthetic process via mevalonate IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum IGI
Inferred from Genetic Interaction
more info
 PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nuclear outer membrane-endoplasmic reticulum membrane network IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
squalene synthase Erg9

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    931002..932472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021271.3 → NP_595363.1  squalene synthase Erg9 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595363.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P36596
    Conserved Domains (1) summary
    TIGR01559
    Location:33 → 374
    squal_synth; farnesyl-diphosphate farnesyltransferase
Nucleotide Protein
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