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scr1 DNA-binding transcription repressor, glucose sensing, Scr1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540768, updated on 18-Sep-2024

Summary

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Official Symbol
scr1
Official Full Name
DNA-binding transcription repressor, glucose sensing, Scr1
Primary source
PomBase:SPBC1D7.02c
Locus tag
SPOM_SPBC1D7.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC1D7.02
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Genomic context

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See scr1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (1752093..1755619)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene prefoldin subunit 1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation and characterization of an invertase and its repressor genes from Schizosaccharomyces pombe. Tanaka N, et al. Biochem Biophys Res Commun, 1998 Apr 7. PMID 9535817
  2. Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress. Schutt KL, et al. Mol Biol Cell, 2017 Jul 1. PMID 28515144, Free PMC Article
  3. Snf1-like protein kinase Ssp2 regulates glucose derepression in Schizosaccharomyces pombe. Matsuzawa T, et al. Eukaryot Cell, 2012 Feb. PMID 22140232, Free PMC Article
  4. Genetic-interaction screens uncover novel biological roles and regulators of transcription factors in fission yeast. Chatfield-Reed K, et al. G3 (Bethesda), 2022 Aug 25. PMID 35924983, Free PMC Article
  5. The gld1+ gene encoding glycerol dehydrogenase is required for glycerol metabolism in Schizosaccharomyces pombe. Matsuzawa T, et al. Appl Microbiol Biotechnol, 2010 Jun. PMID 20396879

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific EXP
Inferred from Experiment
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in carbon catabolite repression of transcription from RNA polymerase II promoter by glucose IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of flocculation EXP
Inferred from Experiment
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm EXP
Inferred from Experiment
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleoplasm EXP
Inferred from Experiment
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcription repressor, glucose sensing, Scr1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1752093..1755619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021615.3 → NP_595717.1  DNA-binding transcription repressor, glucose sensing, Scr1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595717.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O14335
    Conserved Domains (4) summary
    COG5048
    Location:1 → 478
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:28 → 48
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:26 → 48
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:43 → 67
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
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