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prp43 ATP-dependent RNA helicase Prp43 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540057, updated on 14-Nov-2024

Summary

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Official Symbol
prp43
Official Full Name
ATP-dependent RNA helicase Prp43
Primary source
PomBase:SPBC16H5.10c
Locus tag
SPOM_SPBC16H5.10C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See prp43 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2279705..2282239)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein arginine N-methyltransferase Skb1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP-binding cassette sub-family F protein Neighboring gene alpha-1,2-mannosyltransferase Omh2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Co-evolution of spliceosomal disassembly interologs: crowning J-protein component with moonlighting RNA-binding activity. Raut S, et al. Curr Genet, 2019 Apr. PMID 30467716
  2. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article
  3. Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance. Lee NN, et al. Cell, 2013 Nov 21. PMID 24210919, Free PMC Article
  4. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
  5. Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe. Cipakova I, et al. Cell Cycle, 2019 Jul. PMID 31219728, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA helicase activity ISO
Inferred from Sequence Orthology
more info
  
enables helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in rRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in spliceosomal complex disassembly IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of U2-type spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus HDA PubMed 
part_of post-mRNA release spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent RNA helicase Prp43

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2279705..2282239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021845.3 → NP_595937.1  ATP-dependent RNA helicase Prp43 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595937.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42945, Q9USE5
    Conserved Domains (5) summary
    smart00487
    Location:80 → 258
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:482 → 565
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:92 → 232
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:257 → 421
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam07717
    Location:599 → 703
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
Nucleotide Protein
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