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urk1 uridine kinase/uracil phosphoribosyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2538946, updated on 18-Sep-2024

Summary

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Official Symbol
urk1
Official Full Name
uridine kinase/uracil phosphoribosyltransferase
Primary source
PomBase:SPCC162.11c
Locus tag
SPOM_SPCC162.11C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See urk1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (1555999..1557913)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene zinc finger C3HC-type containing RNA export factor Rsm1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TORC1 subunit Tco89 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Ppk33 Neighboring gene 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability. Kriegenburg F, et al. PLoS Genet, 2014 Jan. PMID 24497846, Free PMC Article
  2. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article
  3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
  4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
  5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables cytidine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables uracil phosphoribosyltransferase activity NAS
Non-traceable Author Statement
more info
  
enables uridine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in CTP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in UMP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in pyrimidine nucleobase metabolic process NAS
Non-traceable Author Statement
more info
  
involved_in pyrimidine-containing compound salvage IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
uridine kinase/uracil phosphoribosyltransferase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1555999..1557913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001355921.2 → NP_001342737.1  uridine kinase/uracil phosphoribosyltransferase [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74427
    Conserved Domains (2) summary
    COG0035
    Location:250 → 454
    Upp; Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]
    cd02023
    Location:23 → 220
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
Nucleotide Protein
Heading Accession and Version

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