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CG30423 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246605, updated on 4-Jan-2025

Summary

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Official Symbol
CG30423provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050423
Locus tag
Dmel_CG30423
See related
AllianceGenome:FB:FBgn0050423
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH04491; Dmel\CG30423
Summary
Predicted to enable signaling receptor binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Predicted to be located in Golgi apparatus. Predicted to be active in endosome. Is expressed in adult head and adult heart. Orthologous to human LEPROT (leptin receptor overlapping transcript) and LEPROTL1 (leptin receptor overlapping transcript like 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG30423 in Genome Data Viewer
Location:
60E4-60E4; 2-107 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24874976..24875865, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20762499..20763388, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44829 Neighboring gene Activating transcription factor-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43466 Neighboring gene Na,K-ATPase Interacting

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Genome of Drosophila innubila Reveals Lineage-Specific Patterns of Selection in Immune Genes. Hill T, et al. Mol Biol Evol, 2019 Jul 1. PMID 30865231, Free PMC Article
  2. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article
  3. Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila. Meltzer H, et al. Nat Commun, 2019 May 8. PMID 31068592, Free PMC Article
  4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
  5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables signaling receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG30423-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24874976..24875865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166691.4 → NP_726490.3  uncharacterized protein Dmel_CG30423 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726490.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3DMN9, Q8IGJ6, Q8MMD0
    Conserved Domains (1) summary
    pfam04133
    Location:7 → 121
    Vps55; Vacuolar protein sorting 55
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MMD0 Q8MMD0

Gene LinkOut

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