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UQCR-11L Ubiquinol-cytochrome c reductase 11 kDa subunit-like [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246560, updated on 4-Jan-2025

Summary

Official Symbol
UQCR-11Lprovided by FlyBase
Official Full Name
Ubiquinol-cytochrome c reductase 11 kDa subunit-likeprovided by FlyBase
Primary source
FLYBASE:FBgn0050354
Locus tag
Dmel_CG30354
See related
AllianceGenome:FB:FBgn0050354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG30354; Dmel\CG30354; NEST:bs01g03; UCRH
Summary
Predicted to contribute to ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial intermembrane space. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to human UQCRH (ubiquinol-cytochrome c reductase hinge protein) and UQCRHL (ubiquinol-cytochrome c reductase hinge protein like). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See UQCR-11L in Genome Data Viewer
Location:
44E2-44E2; 2-59 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8677219..8677661)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4564724..4565166)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44281 Neighboring gene patched Neighboring gene Acyl-CoA synthetase long-chain Neighboring gene transfer RNA:Leucine-CAG 1-1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to ubiquinol-cytochrome-c reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial electron transport, ubiquinol to cytochrome c ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in mitochondrial intermembrane space ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of respiratory chain complex III IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of respiratory chain complex III ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
Ubiquinol-cytochrome c reductase 11 kDa subunit-like
Names
CG30354-PA
CG30354-PB
UQCR-11L-PA
UQCR-11L-PB
Ubiquinol-cytochrome C reductase complex 11 kDa protein
Ubiquinol-cytochrome c reductase 11 kDa protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8677219..8677661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273882.1NP_001260811.1  Ubiquinol-cytochrome c reductase 11 kDa subunit-like, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260811.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPY6
    Conserved Domains (1) summary
    pfam02320
    Location:2385
    UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein
  2. NM_165616.3NP_724697.1  Ubiquinol-cytochrome c reductase 11 kDa subunit-like, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724697.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QPY6
    Related
    FBpp0087782
    Conserved Domains (1) summary
    pfam02320
    Location:2385
    UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein