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ppk3 pickpocket 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246504, updated on 9-Dec-2024

Summary

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Official Symbol
ppk3provided by FlyBase
Official Full Name
pickpocket 3provided by FlyBase
Primary source
FLYBASE:FBgn0050181
Locus tag
Dmel_CG30181
See related
AllianceGenome:FB:FBgn0050181
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15872; cg30181; CG30181; Dmel\CG30181
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See ppk3 in Genome Data Viewer
Location:
59E3-59E3; 2-103 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23538631..23540773, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19426154..19428296, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene RabX1 Neighboring gene minus Neighboring gene brown Neighboring gene Gustatory receptor 59e Neighboring gene Gustatory receptor 59f

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of chromatin structure of genes silenced by heterochromatin in trans. Nisha P, et al. Genetics, 2008 May. PMID 18493059, Free PMC Article
  2. TEMPLE: analysing population genetic variation at transcription factor binding sites. Litovchenko M, et al. Mol Ecol Resour, 2016 Nov. PMID 27106869
  3. ppk23-Dependent chemosensory functions contribute to courtship behavior in Drosophila melanogaster. Lu B, et al. PLoS Genet, 2012. PMID 22438833, Free PMC Article
  4. Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Ben-Shahar Y. Adv Genet, 2011. PMID 22099690, Free PMC Article
  5. Evolution of the Insect PPK Gene Family. Latorre-Estivalis JM, et al. Genome Biol Evol, 2021 Sep 1. PMID 34390578, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pickpocket 3
Names
CG30181-PA
ppk3-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23538631..23540773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166606.1 → NP_726336.1  pickpocket 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726336.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MLR6
    Related
    FBpp0072025, FBtr0072116
    Conserved Domains (1) summary
    pfam00858
    Location:59 → 464
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MLR6 Q8MLR6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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