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CG30048 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 246415, updated on 4-Jan-2025

Summary

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Official Symbol
CG30048provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0050048
Locus tag
Dmel_CG30048
See related
AllianceGenome:FB:FBgn0050048
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG30048; Pkd1
Summary
Predicted to be involved in calcium ion transport. Predicted to be part of polycystin complex. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG30048 in Genome Data Viewer
Location:
49A2-49A2; 2-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12394907..12399142)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8282412..8286647)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 49Ad Neighboring gene Odorant receptor 49a Neighboring gene Cuticular protein 49Ae Neighboring gene Cuticular protein 49Af

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural genetic variation in a dopamine receptor is associated with variation in female fertility in Drosophila melanogaster. Lyman RF, et al. Proc Biol Sci, 2023 Apr 12. PMID 37040806, Free PMC Article
  2. Drosophila melanogaster: a simple genetic model of kidney structure, function and disease. Dow JAT, et al. Nat Rev Nephrol, 2022 Jul. PMID 35411063
  3. Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila. Blanco E, et al. Genome Biol, 2008. PMID 18783608, Free PMC Article
  4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in calcium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of polycystin complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG30048-PC
CG30048-PD
CG30048-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12394907..12399142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001414072.1 → NP_001400986.1  uncharacterized protein Dmel_CG30048, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8Z0

  2. NM_165895.4 → NP_725155.4  uncharacterized protein Dmel_CG30048, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725155.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8Y9
    Conserved Domains (2) summary
    pfam02010
    Location:1 → 210
    REJ; REJ domain
    cl00011
    Location:760 → 860
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...

  3. NM_001414073.1 → NP_001401003.1  uncharacterized protein Dmel_CG30048, isoform E [Drosophila melanogaster]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z8Y9 A1Z8Y9
A1Z8Z0 A1Z8Z0

Gene LinkOut

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