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Tmem150a transmembrane protein 150A [ Rattus norvegicus (Norway rat) ]

Gene ID: 245966, updated on 4-Jan-2025

Summary

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Official Symbol
Tmem150aprovided by RGD
Official Full Name
transmembrane protein 150Aprovided by RGD
Primary source
RGD:619998
See related
EnsemblRapid:ENSRNOG00000061100 AllianceGenome:RGD:619998
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tm6p1; Tmem150
Summary
Involved in catabolic process. Predicted to be active in plasma membrane. Orthologous to human TMEM150A (transmembrane protein 150A). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Liver (RPKM 475.5), Kidney (RPKM 407.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem150a in Genome Data Viewer
Location:
4q32
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (105968526..105972822)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (104410271..104414630)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (100217986..100222131)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene surfactant protein B Neighboring gene ubiquitin specific peptidase 39 Neighboring gene similar to human chromosome 2 open reading frame 68 Neighboring gene ring finger protein 181 Neighboring gene vesicle-associated membrane protein 5 Neighboring gene uncharacterized LOC134486592 Neighboring gene vesicle-associated membrane protein 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of a new gene (rat TM6P1) encoding a fasting-inducible, integral membrane protein with six transmembrane domains. Zhang J, et al. Biochim Biophys Acta, 2000 Jun 21. PMID 10858565
  2. Plasticity of PI4KIIIα interactions at the plasma membrane. Chung J, et al. EMBO Rep, 2015 Mar. PMID 25608530, Free PMC Article
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in phosphatidylinositol phosphate biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein localization to plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
transmembrane protein 150A
Names
fasting-inducible integral membrane protein TM6P1
transmembrane protein 150

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_139107.1 → NP_620807.1  transmembrane protein 150A precursor

    See identical proteins and their annotated locations for NP_620807.1

    Status: PROVISIONAL

    Source sequence(s)
    AF186469
    UniProtKB/Swiss-Prot
    Q9QZE9
    UniProtKB/TrEMBL
    A0A8I6APK8, A6IAA6
    Conserved Domains (1) summary
    pfam10277
    Location:3 → 229
    Frag1; Frag1/DRAM/Sfk1 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    105968526..105972822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063285524.1 → XP_063141594.1  transmembrane protein 150A isoform X1

    UniProtKB/Swiss-Prot
    Q9QZE9
    UniProtKB/TrEMBL
    A0A8I6APK8, A6IAA6
    Related
    ENSRNOP00000110592.1, ENSRNOT00000172521.1

  2. XM_006236658.5 → XP_006236720.1  transmembrane protein 150A isoform X1

    See identical proteins and their annotated locations for XP_006236720.1

    UniProtKB/Swiss-Prot
    Q9QZE9
    UniProtKB/TrEMBL
    A0A8I6APK8, A6IAA6
    Conserved Domains (1) summary
    pfam10277
    Location:3 → 229
    Frag1; Frag1/DRAM/Sfk1 family

  3. XM_063285525.1 → XP_063141595.1  transmembrane protein 150A isoform X3

    UniProtKB/TrEMBL
    A0A8I6APK8
    Related
    ENSRNOP00000073089.2, ENSRNOT00000079415.3

  4. XM_017592444.3 → XP_017447933.2  transmembrane protein 150A isoform X2

    UniProtKB/TrEMBL
    A0A8I6APK8
    Conserved Domains (1) summary
    pfam10277
    Location:62 → 228
    Frag1; Frag1/DRAM/Sfk1 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9QZE9.1 GenPept UniProtKB/Swiss-Prot:Q9QZE9

Gene LinkOut

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