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Dytn dystrotelin [ Mus musculus (house mouse) ]

Gene ID: 241073, updated on 27-Nov-2024

Summary

Official Symbol
Dytnprovided by MGI
Official Full Name
dystrotelinprovided by MGI
Primary source
MGI:MGI:2685061
See related
Ensembl:ENSMUSG00000069085 AllianceGenome:MGI:2685061
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm215
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to be active in plasma membrane. Is expressed in several structures, including genitourinary system; liver; neural tube; spleen; and stomach. Orthologous to human DYTN (dystrotelin). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Dytn in Genome Data Viewer
Location:
1 C2; 1 32.31 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (63662010..63726086, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (63622851..63686927, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene a disintegrin and metallopeptidase domain 23 Neighboring gene predicted gene, 22281 Neighboring gene STARR-seq mESC enhancer starr_01142 Neighboring gene family with sequence similarity 237, member A Neighboring gene STARR-seq mESC enhancer starr_01143 Neighboring gene malate dehydrogenase 1B, NAD (soluble) Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:63777041-63777224 Neighboring gene FAST kinase domains 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in synaptic signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081658.1NP_001075127.1  dystrotelin

    See identical proteins and their annotated locations for NP_001075127.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ443727
    Consensus CDS
    CCDS35595.1
    UniProtKB/Swiss-Prot
    A2CI98, Q5F254
    Related
    ENSMUSP00000087787.5, ENSMUST00000090313.5
    Conserved Domains (3) summary
    pfam09068
    Location:9118
    EF-hand_2; EF hand
    pfam09069
    Location:125217
    EF-hand_3; EF-hand
    cl00295
    Location:226274
    ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    63662010..63726086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)