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Ccser1 coiled-coil serine rich 1 [ Mus musculus (house mouse) ]

Gene ID: 232035, updated on 27-Nov-2024

Summary

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Official Symbol
Ccser1provided by MGI
Official Full Name
coiled-coil serine rich 1provided by MGI
Primary source
MGI:MGI:3045354
See related
Ensembl:ENSMUSG00000039578 AllianceGenome:MGI:3045354
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam190a; 6230405M12Rik; C130092O11Rik
Summary
Is expressed in metanephros; nervous system; and trachea. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human CCSER1 (coiled-coil serine rich protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E14 (RPKM 2.1), whole brain E14.5 (RPKM 2.0) and 18 other tissues See more
Orthologs
human all
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Genomic context

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See Ccser1 in Genome Data Viewer
Location:
6 B3; 6 29.24 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (61156942..62359847)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (61179960..62382863)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_16065 Neighboring gene STARR-seq mESC enhancer starr_16066 Neighboring gene STARR-seq mESC enhancer starr_16068 Neighboring gene multimerin 1 Neighboring gene STARR-seq mESC enhancer starr_16076 Neighboring gene protein phosphatase 6, catalytic subunit pseudogene Neighboring gene RIKEN cDNA A730020E08 gene Neighboring gene STARR-seq mESC enhancer starr_16079 Neighboring gene STARR-seq mESC enhancer starr_16080 Neighboring gene STARR-seq mESC enhancer starr_16081 Neighboring gene STARR-seq mESC enhancer starr_16082 Neighboring gene STARR-seq mESC enhancer starr_16083 Neighboring gene STARR-seq mESC enhancer starr_16084 Neighboring gene STARR-seq mESC enhancer starr_16085 Neighboring gene STARR-seq mESC enhancer starr_16086 Neighboring gene STARR-seq mESC enhancer starr_16087 Neighboring gene STARR-seq mESC enhancer starr_16088 Neighboring gene STARR-seq mESC enhancer starr_16089 Neighboring gene STARR-seq mESC enhancer starr_16090 Neighboring gene STARR-seq mESC enhancer starr_16091 Neighboring gene STARR-seq mESC enhancer starr_16092 Neighboring gene STARR-seq mESC enhancer starr_16093 Neighboring gene STARR-seq mESC enhancer starr_16094 Neighboring gene STARR-seq mESC enhancer starr_16095 Neighboring gene phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase pseudogene Neighboring gene STARR-seq mESC enhancer starr_16096 Neighboring gene sprouty homolog 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. CircFam190a: a critical positive regulator of osteoclast differentiation via enhancement of the AKT1/HSP90β complex. Chen K, et al. Exp Mol Med, 2023 Sep. PMID 37653038, Free PMC Article
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CircFam190a: a critical positive regulator of osteoclast differentiation via enhancement of the AKT1/HSP90beta complex.
    Title: CircFam190a: a critical positive regulator of osteoclast differentiation via enhancement of the AKT1/HSP90β complex.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • MGC130404, MGC130405

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
serine-rich coiled-coil domain-containing protein 1
Names
coiled-coil serine-rich protein 1
family with sequence similarity 190, member A
protein FAM190A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164316.1 → NP_001157788.1  serine-rich coiled-coil domain-containing protein 1

    See identical proteins and their annotated locations for NP_001157788.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK031754, AK173231, BB634602, BB646598
    Consensus CDS
    CCDS51800.1
    UniProtKB/Swiss-Prot
    Q3KN97, Q69ZD5, Q8C0C4, Q8C822
    Related
    ENSMUSP00000040251.7, ENSMUST00000045522.13

  2. NM_183310.2 → NP_899133.2  serine-rich coiled-coil domain-containing protein 1

    See identical proteins and their annotated locations for NP_899133.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK173231, BB634602, BB646598, BC107398
    Consensus CDS
    CCDS51800.1
    UniProtKB/Swiss-Prot
    Q3KN97, Q69ZD5, Q8C0C4, Q8C822
    Related
    ENSMUSP00000122894.2, ENSMUST00000126214.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    61156942..62359847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036166046.1 → XP_036021939.1  serine-rich coiled-coil domain-containing protein 1 isoform X3

  2. XM_011241297.4 → XP_011239599.1  serine-rich coiled-coil domain-containing protein 1 isoform X4

  3. XM_006505955.3 → XP_006506018.1  serine-rich coiled-coil domain-containing protein 1 isoform X2

  4. XM_006505954.3 → XP_006506017.1  serine-rich coiled-coil domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q8C0C4
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C0C4.2 GenPept UniProtKB/Swiss-Prot:Q8C0C4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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