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Cep15 centrosomal protein 15 [ Mus musculus (house mouse) ]

Gene ID: 218734, updated on 27-Nov-2024

Summary

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Official Symbol
Cep15provided by MGI
Official Full Name
centrosomal protein 15provided by MGI
Primary source
MGI:MGI:1917937
See related
Ensembl:ENSMUSG00000033111 AllianceGenome:MGI:1917937
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3830406C13Rik
Summary
Predicted to be located in cilium. Orthologous to human CEP15 (centrosomal protein 15). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bladder adult (RPKM 3.5), testis adult (RPKM 2.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Cep15 in Genome Data Viewer
Location:
14 A1; 14 6.34 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (10147278..10185610, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (12284153..12324492)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35954 Neighboring gene predicted gene, 24578 Neighboring gene Fez family zinc finger 2 Neighboring gene protein tyrosine phosphatase receptor type G Neighboring gene STARR-seq mESC enhancer starr_35952 Neighboring gene STARR-seq mESC enhancer starr_35951 Neighboring gene predicted gene, 53822 Neighboring gene STARR-seq mESC enhancer starr_35947 Neighboring gene STARR-seq mESC enhancer starr_35940 Neighboring gene STARR-seq mESC enhancer starr_35939 Neighboring gene STARR-seq mESC enhancer starr_35937 Neighboring gene predicted gene, 52128

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC36213, 3110059I09Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
centrosomal protein 15
Names
centrosomal protein 15 kDa
uncharacterized protein C3orf14 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001284383.1 → NP_001271312.1  centrosomal protein 15 isoform 2

    See identical proteins and their annotated locations for NP_001271312.1

    Status: VALIDATED

    Source sequence(s)
    AC154682, AI931548, AK076182, AK078647, AV151510, BY233185
    Consensus CDS
    CCDS26817.1
    UniProtKB/Swiss-Prot
    Q6PFA6, Q8BGD0, Q8R061
    UniProtKB/TrEMBL
    A0A286YD67
    Related
    ENSMUSP00000153287.2, ENSMUST00000223762.2
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  2. NM_001284384.1 → NP_001271313.1  centrosomal protein 15 isoform 2

    See identical proteins and their annotated locations for NP_001271313.1

    Status: VALIDATED

    Source sequence(s)
    AC154682, AI931548, AK076182, AK078647, AV151510, BY073949, BY233185
    Consensus CDS
    CCDS26817.1
    UniProtKB/Swiss-Prot
    Q6PFA6, Q8BGD0, Q8R061
    UniProtKB/TrEMBL
    A0A286YD67
    Related
    ENSMUSP00000153430.2, ENSMUST00000224389.2
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  3. NM_001284385.1 → NP_001271314.1  centrosomal protein 15 isoform 2

    See identical proteins and their annotated locations for NP_001271314.1

    Status: VALIDATED

    Source sequence(s)
    AC154682, AK076182, AK078647, AV151510, BY073949
    Consensus CDS
    CCDS26817.1
    UniProtKB/Swiss-Prot
    Q6PFA6, Q8BGD0, Q8R061
    UniProtKB/TrEMBL
    A0A286YD67
    Related
    ENSMUSP00000153402.2, ENSMUST00000225294.2
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  4. NM_001284386.1 → NP_001271315.1  centrosomal protein 15 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC154682, AK076182, AK078647, AV151510
    UniProtKB/Swiss-Prot
    Q8BGD0
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 86
    DUF4570; Domain of unknown function (DUF4570)

  5. NM_001284387.1 → NP_001271316.1  centrosomal protein 15 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC154682, AK076182, AK078647, AV151510, BE624571
    UniProtKB/TrEMBL
    A0A286YDP6
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 86
    DUF4570; Domain of unknown function (DUF4570)

  6. NM_001379567.1 → NP_001366496.1  centrosomal protein 15 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC154682
    UniProtKB/TrEMBL
    A0A286YDP6
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  7. NM_001379568.1 → NP_001366497.1  centrosomal protein 15 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC154682
    UniProtKB/TrEMBL
    A0A286YDP6
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  8. NM_001379569.1 → NP_001366498.1  centrosomal protein 15 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154682
    UniProtKB/Swiss-Prot
    Q6PFA6, Q8BGD0, Q8R061
    UniProtKB/TrEMBL
    A0A286YD67
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  9. NM_146051.3 → NP_666163.1  centrosomal protein 15 isoform 1

    See identical proteins and their annotated locations for NP_666163.1

    Status: VALIDATED

    Source sequence(s)
    AC154682, AK076182, AK078647, AV151510
    Consensus CDS
    CCDS36805.1
    UniProtKB/Swiss-Prot
    Q8BGD0
    Related
    ENSMUSP00000108288.4, ENSMUST00000112669.10
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 84
    DUF4570; Domain of unknown function (DUF4570)

  10. NM_178141.3 → NP_835277.1  centrosomal protein 15 isoform 2

    See identical proteins and their annotated locations for NP_835277.1

    Status: VALIDATED

    Source sequence(s)
    AC154682, AK076182, AK078647, AV151510
    Consensus CDS
    CCDS26817.1
    UniProtKB/Swiss-Prot
    Q6PFA6, Q8BGD0, Q8R061
    UniProtKB/TrEMBL
    A0A286YD67
    Related
    ENSMUSP00000126960.2, ENSMUST00000163392.3
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    10147278..10185610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517987.5 → XP_006518050.1  centrosomal protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006518050.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  2. XM_006517989.5 → XP_006518052.1  centrosomal protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006518052.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  3. XM_006517995.4 → XP_006518058.1  centrosomal protein 15 isoform X4

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 87
    DUF4570; Domain of unknown function (DUF4570)

  4. XM_006517988.5 → XP_006518051.1  centrosomal protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006518051.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  5. XM_006517991.5 → XP_006518054.1  centrosomal protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006518054.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  6. XM_006517990.5 → XP_006518053.1  centrosomal protein 15 isoform X1

    See identical proteins and their annotated locations for XP_006518053.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  7. XM_036158545.1 → XP_036014438.1  centrosomal protein 15 isoform X5

    Conserved Domains (1) summary
    pfam15134
    Location:36 → 86
    DUF4570; Domain of unknown function (DUF4570)

  8. XM_030247731.2 → XP_030103591.1  centrosomal protein 15 isoform X2

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  9. XM_036158546.1 → XP_036014439.1  centrosomal protein 15 isoform X6

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  10. XM_036158543.1 → XP_036014436.1  centrosomal protein 15 isoform X2

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  11. XM_006517997.2 → XP_006518060.1  centrosomal protein 15 isoform X6

    See identical proteins and their annotated locations for XP_006518060.1

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  12. XM_006517992.2 → XP_006518055.1  centrosomal protein 15 isoform X2

    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  13. XM_006517993.3 → XP_006518056.1  centrosomal protein 15 isoform X3

    See identical proteins and their annotated locations for XP_006518056.1

    UniProtKB/TrEMBL
    A0A286YDP6
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  14. XM_030247732.1 → XP_030103592.1  centrosomal protein 15 isoform X3

    UniProtKB/TrEMBL
    A0A286YDP6
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

  15. XM_036158544.1 → XP_036014437.1  centrosomal protein 15 isoform X3

    UniProtKB/TrEMBL
    A0A286YDP6
    Related
    ENSMUSP00000153330.2, ENSMUST00000223702.2
    Conserved Domains (1) summary
    pfam15134
    Location:1 → 110
    DUF4570; Domain of unknown function (DUF4570)

RNA

  1. XR_874030.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BGD0.1 GenPept UniProtKB/Swiss-Prot:Q8BGD0

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