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Hbq1a hemoglobin, theta 1A [ Mus musculus (house mouse) ]

Gene ID: 216635, updated on 27-Nov-2024

Summary

Official Symbol
Hbq1aprovided by MGI
Official Full Name
hemoglobin, theta 1Aprovided by MGI
Primary source
MGI:MGI:2685722
See related
Ensembl:ENSMUSG00000020295 AllianceGenome:MGI:2685722
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hbq1; Gm876; Hbqt2; A230090E05Rik
Summary
This gene is one of two mouse theta-globin genes found in the alpha-globin gene cluster on chromosome 11. This gene represents the T2 (or 3') theta-globin gene described in PMIDs 18245844 and 11157800, respectively. [provided by RefSeq, Apr 2009]
Expression
Biased expression in liver E14.5 (RPKM 26.4), liver E14 (RPKM 22.2) and 5 other tissues See more
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Genomic context

See Hbq1a in Genome Data Viewer
Location:
11 A4; 11 18.87 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32250069..32250873)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32300069..32300873)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene hemoglobin, theta 1B Neighboring gene hemoglobin alpha, adult chain 2 Neighboring gene predicted gene, 46275 Neighboring gene STARR-seq mESC enhancer starr_29106 Neighboring gene SH3 and PX domains 2B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to haptoglobin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables oxygen binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables oxygen carrier activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in hydrogen peroxide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of haptoglobin-hemoglobin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of hemoglobin complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
hemoglobin, theta T2
Names
Hbq1 3'-theta
hemoglobin, theta 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175000.2NP_778165.1  hemoglobin, theta T2

    See identical proteins and their annotated locations for NP_778165.1

    Status: PROVISIONAL

    Source sequence(s)
    AK039049
    Consensus CDS
    CCDS24525.1
    UniProtKB/TrEMBL
    B9EIX8, Q8BYM1
    Related
    ENSMUSP00000020535.2, ENSMUST00000020535.2
    Conserved Domains (1) summary
    cl21461
    Location:4121
    Globin_like; Globin-like proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    32250069..32250873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)