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Slc44a3 solute carrier family 44, member 3 [ Mus musculus (house mouse) ]

Gene ID: 213603, updated on 27-Nov-2024

Summary

Official Symbol
Slc44a3provided by MGI
Official Full Name
solute carrier family 44, member 3provided by MGI
Primary source
MGI:MGI:2384860
See related
Ensembl:ENSMUSG00000039865 AllianceGenome:MGI:2384860
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in gut and olfactory epithelium. Orthologous to human SLC44A3 (solute carrier family 44 member 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in colon adult (RPKM 11.7), adrenal adult (RPKM 10.2) and 17 other tissues See more
Orthologs
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Genomic context

See Slc44a3 in Genome Data Viewer
Location:
3 G1; 3 52.94 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (121253177..121325993, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (121459528..121532344, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40134 Neighboring gene STARR-seq mESC enhancer starr_08841 Neighboring gene STARR-seq mESC enhancer starr_08842 Neighboring gene STARR-positive B cell enhancer mm9_chr3:121129235-121129536 Neighboring gene calponin 3, acidic Neighboring gene RIKEN cDNA A530020G20 gene Neighboring gene STARR-positive B cell enhancer mm9_chr3:121238792-121239093 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:121250785-121250968 Neighboring gene STARR-seq mESC enhancer starr_08854 Neighboring gene STARR-seq mESC enhancer starr_08855 Neighboring gene STARR-seq mESC enhancer starr_08856 Neighboring gene predicted gene, 33547 Neighboring gene predicted gene, 33485 Neighboring gene predicted gene, 33708

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC18084, MGC38127

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables organic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in organic cation transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
choline transporter-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145394.3NP_663369.2  choline transporter-like protein 3

    See identical proteins and their annotated locations for NP_663369.2

    Status: VALIDATED

    Source sequence(s)
    AA450663, AC105336, AC115727, AK194277, BB859851, BY735109, CJ094004, CJ130557, CO813168
    Consensus CDS
    CCDS51060.1
    UniProtKB/Swiss-Prot
    G5E8A3, Q921V7
    Related
    ENSMUSP00000040210.8, ENSMUST00000039197.9
    Conserved Domains (1) summary
    pfam04515
    Location:291604
    Choline_transpo; Plasma-membrane choline transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    121253177..121325993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)