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Szrd1 SUZ RNA binding domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 213491, updated on 27-Nov-2024

Summary

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Official Symbol
Szrd1provided by MGI
Official Full Name
SUZ RNA binding domain containing 1provided by MGI
Primary source
MGI:MGI:1098672
See related
Ensembl:ENSMUSG00000040842 AllianceGenome:MGI:1098672
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D4Ertd22e; 1110022I03
Summary
Orthologous to human SZRD1 (SUZ RNA binding domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in adrenal adult (RPKM 23.3), duodenum adult (RPKM 22.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Szrd1 in Genome Data Viewer
Location:
4 D3; 4 73.38 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (140840326..140867110, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141112978..141139799, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S2 pseudogene Neighboring gene spermatogenesis associated 21 Neighboring gene STARR-seq mESC enhancer starr_11890 Neighboring gene STARR-positive B cell enhancer ABC_E3533 Neighboring gene STARR-positive B cell enhancer ABC_E3534 Neighboring gene F-box protein 42 Neighboring gene STARR-seq mESC enhancer starr_11892 Neighboring gene STARR-positive B cell enhancer ABC_E10273 Neighboring gene STARR-positive B cell enhancer ABC_E3535 Neighboring gene STARR-positive B cell enhancer ABC_E6249 Neighboring gene ciliogenesis and planar polarity effector 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article
  2. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  3. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
SUZ RNA-binding domain-containing; SUZ domain-containing protein 1
Names
UPF0485 protein C1orf144 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025608.3 → NP_001020779.1  SUZ RNA-binding domain-containing isoform 1

    See identical proteins and their annotated locations for NP_001020779.1

    Status: VALIDATED

    Source sequence(s)
    AL645625
    Consensus CDS
    CCDS18864.1
    UniProtKB/Swiss-Prot
    Q3TB72, Q6NXN1, Q8BT36
    UniProtKB/TrEMBL
    A2AA85
    Related
    ENSMUSP00000099545.4, ENSMUST00000102487.4
    Conserved Domains (2) summary
    pfam12752
    Location:56 → 107
    SUZ; SUZ domain
    pfam12901
    Location:119 → 151
    SUZ-C; SUZ-C motif

  2. NM_001277195.2 → NP_001264124.1  SUZ RNA-binding domain-containing isoform 3

    See identical proteins and their annotated locations for NP_001264124.1

    Status: VALIDATED

    Source sequence(s)
    AL645625
    UniProtKB/TrEMBL
    A2AA85
    Related
    ENSMUSP00000115949.2, ENSMUST00000148204.8
    Conserved Domains (2) summary
    pfam12752
    Location:55 → 106
    SUZ; SUZ domain
    pfam12901
    Location:118 → 150
    SUZ-C; SUZ-C motif

RNA

  1. NR_102343.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL645625
    Related
    ENSMUST00000094549.11

  2. NR_102344.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL645625
    Related
    ENSMUST00000039939.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    140840326..140867110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253383.1 → XP_030109243.1  SUZ domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    pfam12752
    Location:55 → 106
    SUZ; SUZ domain

  2. XM_006538700.3 → XP_006538763.1  SUZ domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A2AA85
    Conserved Domains (2) summary
    pfam12752
    Location:48 → 99
    SUZ; SUZ domain
    pfam12901
    Location:127 → 143
    SUZ-C; SUZ-C motif

  3. XM_006538699.5 → XP_006538762.1  SUZ domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A2AA85
    Conserved Domains (2) summary
    pfam12752
    Location:49 → 100
    SUZ; SUZ domain
    pfam12901
    Location:128 → 144
    SUZ-C; SUZ-C motif

  4. XM_006538695.5 → XP_006538758.1  SUZ domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A2AA85
    Conserved Domains (2) summary
    pfam12752
    Location:63 → 114
    SUZ; SUZ domain
    pfam12901
    Location:142 → 158
    SUZ-C; SUZ-C motif

  5. XM_006538694.5 → XP_006538757.1  SUZ domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A2AA85
    Conserved Domains (2) summary
    pfam12752
    Location:64 → 115
    SUZ; SUZ domain
    pfam12901
    Location:143 → 159
    SUZ-C; SUZ-C motif

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_174996.2: Suppressed sequence

    Description
    NM_174996.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NXN1.1 GenPept UniProtKB/Swiss-Prot:Q6NXN1

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