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Fam149a family with sequence similarity 149, member A [ Mus musculus (house mouse) ]

Gene ID: 212326, updated on 4-Jan-2025

Summary

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Official Symbol
Fam149aprovided by MGI
Official Full Name
family with sequence similarity 149, member Aprovided by MGI
Primary source
MGI:MGI:2387177
See related
Ensembl:ENSMUSG00000070044 AllianceGenome:MGI:2387177
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA4166
Summary
Is expressed in renal calyx. Orthologous to human FAM149A (family with sequence similarity 149 member A). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Ubiquitous expression in kidney adult (RPKM 6.4), bladder adult (RPKM 4.2) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Fam149a in Genome Data Viewer
Location:
8 B1.1; 8 25.25 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (45789752..45835328, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (45336715..45382291, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30504 Neighboring gene kallikrein B, plasma 1 Neighboring gene cytochrome P450, family 4, subfamily v, polypeptide 3 Neighboring gene STARR-seq mESC enhancer starr_21371 Neighboring gene toll-like receptor 3 Neighboring gene sorbin and SH3 domain containing 2 Neighboring gene predicted gene, 30759

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

General gene information

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Markers

Homology

Clone Names

  • KIAA4166, MGC40851

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM149A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153535.2 → NP_705763.1  protein FAM149A

    See identical proteins and their annotated locations for NP_705763.1

    Status: VALIDATED

    Source sequence(s)
    AK140440, AK141607, BB183041
    Consensus CDS
    CCDS22277.1
    UniProtKB/Swiss-Prot
    Q8CFV2
    Related
    ENSMUSP00000091245.7, ENSMUST00000093526.13
    Conserved Domains (1) summary
    pfam12516
    Location:306 → 369
    DUF3719; Protein of unknown function (DUF3719)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    45789752..45835328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242184.2 → XP_011240486.1  protein FAM149A isoform X1

    Conserved Domains (2) summary
    PRK12323
    Location:56 → 282
    PRK12323; DNA polymerase III subunit gamma/tau
    pfam12516
    Location:306 → 370
    DUF3719; Protein of unknown function (DUF3719)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CFV2.1 GenPept UniProtKB/Swiss-Prot:Q8CFV2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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