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Plac9 placenta specific 9 [ Mus musculus (house mouse) ]

Gene ID: 211623, updated on 27-Nov-2024

Summary

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Official Symbol
Plac9provided by MGI
Official Full Name
placenta specific 9provided by MGI
Primary source
MGI:MGI:2663998
See related
Ensembl:ENSMUSG00000095304 AllianceGenome:MGI:2663998
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm9780; Plac9a; Plac9b; Gm10393
Summary
Predicted to be located in extracellular region. Is expressed in several structures, including brain; foregut; genitourinary system; respiratory system; and submandibular gland primordium. Orthologous to human PLAC9 (placenta associated 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in lung adult (RPKM 185.1), subcutaneous fat pad adult (RPKM 170.7) and 17 other tissues See more
Orthologs
human all
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Genomic context

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See Plac9 in Genome Data Viewer
Location:
14 A3; 14 15.41 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (25888356..25903339, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (25888403..25902893, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_36222 Neighboring gene zinc finger, CCHC domain containing 24 Neighboring gene STARR-positive B cell enhancer mm9_chr14:26567064-26567365 Neighboring gene STARR-seq mESC enhancer starr_36224 Neighboring gene STARR-seq mESC enhancer starr_36226 Neighboring gene STARR-seq mESC enhancer starr_36227 Neighboring gene annexin A11 Neighboring gene predicted gene, 57811 Neighboring gene transmembrane protein 254 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Placenta-specific 9, a putative secretory protein, induces G2/M arrest and inhibits the proliferation of human embryonic hepatic cells. Ouyang C, et al. Biosci Rep, 2018 Dec 21. PMID 30291214, Free PMC Article
  2. Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis. Galaviz-Hernandez C, et al. Gene, 2003 May 8. PMID 12758124
  3. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Naiman N, et al. Dev Cell, 2017 May 22. PMID 28535371, Free PMC Article
  4. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  5. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Abonnenc M, et al. Circ Res, 2013 Oct 25. PMID 24006456

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC41689

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
placenta-specific protein 9
Names
placenta specific 9a
placenta specific 9b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207229.3 → NP_997112.1  placenta-specific protein 9 precursor

    See identical proteins and their annotated locations for NP_997112.1

    Status: VALIDATED

    Source sequence(s)
    AC165285
    Consensus CDS
    CCDS36832.1
    UniProtKB/Swiss-Prot
    Q3V2D9, Q8K262
    Related
    ENSMUSP00000056665.8, ENSMUST00000052286.16
    Conserved Domains (1) summary
    pfam15205
    Location:37 → 106
    PLAC9; Placenta-specific protein 9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    25888356..25903339 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001270503.1: Suppressed sequence

    Description
    NM_001270503.1: This RefSeq was removed because it was redundant with NM_207229.1 after a merge.

  2. NM_001374766.1: Suppressed sequence

    Description
    NM_001374766.1: This RefSeq was removed because it was redundant with NM_207229.1 after a merge.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K262.1 GenPept UniProtKB/Swiss-Prot:Q8K262

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials