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Tmem132c transmembrane protein 132C [ Mus musculus (house mouse) ]

Gene ID: 208213, updated on 27-Nov-2024

Summary

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Official Symbol
Tmem132cprovided by MGI
Official Full Name
transmembrane protein 132Cprovided by MGI
Primary source
MGI:MGI:2443061
See related
Ensembl:ENSMUSG00000034324 AllianceGenome:MGI:2443061
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3230401P16; 2810482M11Rik; 4632425D07Rik
Summary
Predicted to be involved in negative regulation of phosphatase activity. Predicted to be located in membrane. Is expressed in several structures, including central nervous system; jaw; sensory organ; skin; and surface ectoderm. Orthologous to human TMEM132C (transmembrane protein 132C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in limb E14.5 (RPKM 9.3), subcutaneous fat pad adult (RPKM 6.5) and 10 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem132c in Genome Data Viewer
Location:
5 G1.2; 5 65.4 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (127318890..127642854)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (127241826..127565790)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930572K03 gene Neighboring gene RIKEN cDNA 4930548G05 gene Neighboring gene STARR-seq mESC enhancer starr_14399 Neighboring gene transmembrane protein 132C, opposite strand Neighboring gene predicted gene, 54294 Neighboring gene STARR-seq mESC enhancer starr_14401 Neighboring gene STARR-seq mESC enhancer starr_14404 Neighboring gene STARR-seq mESC enhancer starr_14405 Neighboring gene solute carrier family 15, member 4 Neighboring gene STARR-seq mESC enhancer starr_14412 Neighboring gene STARR-seq mESC enhancer starr_14414 Neighboring gene glycosyltransferase 1 domain containing 1 Neighboring gene transmembrane protein 132D Neighboring gene STARR-seq mESC enhancer starr_14415 Neighboring gene STARR-seq mESC enhancer starr_14419

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Differential expression of the Tmem132 family genes in the developing mouse nervous system. Wang Y, et al. Gene Expr Patterns, 2022 Sep. PMID 35690356, Free PMC Article
  2. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in negative regulation of phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 132C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175432.3 → NP_780641.2  transmembrane protein 132C precursor

    Status: VALIDATED

    Source sequence(s)
    AK028289, AK028541, AK157823
    Consensus CDS
    CCDS51650.1
    UniProtKB/Swiss-Prot
    Q8BS69, Q8CEF9
    UniProtKB/TrEMBL
    E9QP73
    Related
    ENSMUSP00000113090.2, ENSMUST00000119026.8
    Conserved Domains (3) summary
    pfam15705
    Location:58 → 187
    TMEM132D_N; Mature oligodendrocyte transmembrane protein, TMEM132D, N-term
    pfam15706
    Location:892 → 980
    TMEM132D_C; Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
    pfam16070
    Location:444 → 786
    TMEM132; Transmembrane protein family 132

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    127318890..127642854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CEF9.3 GenPept UniProtKB/Swiss-Prot:Q8CEF9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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