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CG44247 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 19835727, updated on 9-Dec-2024

Summary

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Official Symbol
CG44247provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0265182
Locus tag
Dmel_CG44247
See related
AllianceGenome:FB:FBgn0265182
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Atf-2; CG30420; CG3749; Dmel\CG44247; FBgn0050420
Summary
Predicted to be located in membrane. Is expressed in several structures, including CNS surface glial cell; antennal disc; embryonic/larval dorsal vessel; presumptive arista; and wing pouch. Orthologous to human NPDC1 (neural proliferation, differentiation and control 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG44247 in Genome Data Viewer
Location:
60E4-60E5; 2-107 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24876691..24881221)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20764214..20768744)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Activating transcription factor-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR43466 Neighboring gene Na,K-ATPase Interacting Neighboring gene Ance-5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of Drosophila A-type lamin C initially causes tendon abnormality including disintegration of cytoskeleton and nuclear lamina in muscular defects. Uchino R, et al. Dev Biol, 2013 Jan 1. PMID 22982669
  2. Canalization of gene expression is a major signature of regulatory cold adaptation in temperate Drosophila melanogaster. von Heckel K, et al. BMC Genomics, 2016 Aug 8. PMID 27502401, Free PMC Article
  3. Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis. Clemente-Ruiz M, et al. Dev Cell, 2016 Feb 8. PMID 26859353
  4. Pilot RNAi Screen in Drosophila Neural Stem Cell Lineages to Identify Novel Tumor Suppressor Genes Involved in Asymmetric Cell Division. Manzanero-Ortiz S, et al. Int J Mol Sci, 2021 Oct 20. PMID 34768763, Free PMC Article
  5. Toward a Consensus in the Repertoire of Hemocytes Identified in Drosophila. Cattenoz PB, et al. Front Cell Dev Biol, 2021. PMID 33748138, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG44247-PA
CG44247-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    24876691..24881221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_138130.4 → NP_611974.2  uncharacterized protein Dmel_CG44247, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611974.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95TP1, Q9W0Z3, Q9W0Z5
    Conserved Domains (1) summary
    pfam06809
    Location:329 → 459
    NPDC1; Neural proliferation differentiation control-1 protein (NPDC1)

  2. NM_166690.3 → NP_726489.2  uncharacterized protein Dmel_CG44247, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726489.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95TP1, Q9W0Z3, Q9W0Z5
    Conserved Domains (1) summary
    pfam06809
    Location:329 → 459
    NPDC1; Neural proliferation differentiation control-1 protein (NPDC1)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W0Z5 Q9W0Z5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials