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CG45071 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 19834908, updated on 9-Dec-2024

Summary

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Official Symbol
CG45071provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0266441
Locus tag
Dmel_CG45071
See related
AllianceGenome:FB:FBgn0266441
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6854; Dmel\CG45071; FBgn0036478; Polypeptide A
Summary
Predicted to enable DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including dorsal ectoderm anlage; ganglia; larval nervous system; and ventral nerve cord primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG45071 in Genome Data Viewer
Location:
71B4-71B5; 3-42 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15105882..15110730)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15098982..15103830)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43973 Neighboring gene CTP synthase Neighboring gene pseudo Neighboring gene antisense RNA:CR43971 Neighboring gene uncharacterized protein Neighboring gene Centrosomal protein 135kDa Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Only one isoform of Drosophila melanogaster CTP synthase forms the cytoophidium. Azzam G, et al. PLoS Genet, 2013. PMID 23459760, Free PMC Article
  2. Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Song H, et al. Genes Dev, 2010 May. PMID 20439429, Free PMC Article
  3. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
  4. The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Bhaskar V, et al. Gene, 2002 Oct 16. PMID 12459265
  5. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG45071-PA
CG45071-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    15105882..15110730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168607.2 → NP_730024.1  uncharacterized protein Dmel_CG45071, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730024.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T055, Q9VUK9
    Conserved Domains (2) summary
    smart00595
    Location:14 → 106
    MADF; subfamily of SANT domain
    pfam02944
    Location:384 → 418
    BESS; BESS motif

  2. NM_001300139.1 → NP_001287068.1  uncharacterized protein Dmel_CG45071, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287068.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J927
    Conserved Domains (2) summary
    pfam02944
    Location:334 → 368
    BESS; BESS motif
    cl23759
    Location:14 → 58
    GT1; GT1, myb-like, SANT family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VUK9 Q9VUK9
X2J927 X2J927

Gene LinkOut

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Other Literature Sources
Molecular Biology Databases
Research Materials