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tsp-4 Tetraspanin [ Caenorhabditis elegans ]

Gene ID: 192060, updated on 2-Nov-2024

Summary

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Official Symbol
tsp-4
Official Full Name
Tetraspanin
Primary source
WormBase:WBGene00006630
Locus tag
CELE_F53B2.2
See related
AllianceGenome:WB:WBGene00006630
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including TSPAN1 (tetraspanin 1); TSPAN18 (tetraspanin 18); and TSPAN2 (tetraspanin 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tsp-4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (12519119..12520250, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Serpentine Receptor, class U Neighboring gene ncRNA Neighboring gene Protein eak-4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tetraspanin
NP_502396.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12519119..12520250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069995.4 → NP_502396.2  Tetraspanin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502396.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20707
    Conserved Domains (2) summary
    cd03127
    Location:116 → 191
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:11 → 223
    Tetraspannin; Tetraspanin family
Nucleotide Protein
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