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sra-4 Serpentine receptor class alpha-4 [ Caenorhabditis elegans ]

Gene ID: 191775, updated on 4-Jan-2025

Summary

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Official Symbol
sra-4
Official Full Name
Serpentine receptor class alpha-4
Primary source
WormBase:WBGene00005030
Locus tag
CELE_AH6.8
See related
AllianceGenome:WB:WBGene00005030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Is expressed in nervous system and pharynx. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sra-4 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (9541601..9542885, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class alpha-8 Neighboring gene Serpentine receptor class alpha-3 Neighboring gene Serpentine receptor class alpha-7 Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development. Battu G, et al. Development, 2003 Jun. PMID 12736202
  2. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Troemel ER, et al. Cell, 1995 Oct 20. PMID 7585938
  3. Identification of a nematode chemosensory gene family. Chen N, et al. Proc Natl Acad Sci U S A, 2005 Jan 4. PMID 15618405, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Serpentine receptor class alpha-4
NP_496049.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9541601..9542885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063648.2 → NP_496049.1  Serpentine receptor class alpha-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496049.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q09206
    Conserved Domains (1) summary
    pfam02117
    Location:1 → 328
    7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q09206.1

Gene LinkOut

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