ncx-5 Sodium/calcium exchanger membrane region domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Official Symbol: ncx-5
Official Full Name: Sodium/calcium exchanger membrane region domain-containing protein
Primary source: WormBase:WBGene00003570
Locus tag: CELE_Y32F6B.2
See related: AllianceGenome:WB:WBGene00003570
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Predicted to be involved in calcium ion transmembrane transport and intracellular calcium ion homeostasis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in oxygen sensory neurons. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Orthologous to human SLC24A1 (solute carrier family 24 member 1) and SLC24A2 (solute carrier family 24 member 2). [provided by Alliance of Genome Resources, Jan 2025]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables antiporter activity	IEA Inferred from Electronic Annotation more info
enables calcium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium, potassium:sodium antiporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in calcium ion transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in calcium ion transport	IEA Inferred from Electronic Annotation more info
involved_in intracellular calcium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in potassium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: Sodium/calcium exchanger membrane region domain-containing protein

NP_505690.2

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain