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ZK1128.7 SHSP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191528, updated on 4-Jan-2025

Summary

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Official Symbol
ZK1128.7
Official Full Name
SHSP domain-containing protein
Primary source
WormBase:WBGene00014233
Locus tag
CELE_ZK1128.7
See related
AllianceGenome:WB:WBGene00014233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be active in cytoplasm and nucleus. Is expressed in vulval muscle. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ZK1128.7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
5
Sequence:
Chromosome: III; NC_003281.10 (10137006..10139124)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to heat IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SHSP domain-containing protein
NP_499252.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10137006..10139124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066851.4 → NP_499252.2  SHSP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499252.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EF99
    Conserved Domains (1) summary
    cd06526
    Location:96 → 178
    metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
Nucleotide Protein
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