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ZC262.5 Putative ATP synthase subunit epsilon, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 191132, updated on 4-Jan-2025

Summary

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Official Symbol
ZC262.5
Official Full Name
Putative ATP synthase subunit epsilon, mitochondrial
Primary source
WormBase:WBGene00022582
Locus tag
CELE_ZC262.5
See related
AllianceGenome:WB:WBGene00022582
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be part of proton-transporting ATP synthase complex, catalytic core F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Orthologous to human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ZC262.5 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (8342224..8342610, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class M Neighboring gene pseudo Neighboring gene Kinesin motor domain-containing protein Neighboring gene Cytochrome C biogenesis protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of proton-transporting ATP synthase complex, catalytic core F(1) IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative ATP synthase subunit epsilon, mitochondrial
NP_498839.1
  • Predicted

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8342224..8342610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066438.1 → NP_498839.1  Putative ATP synthase subunit epsilon, mitochondrial [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498839.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34539
    Conserved Domains (1) summary
    pfam04627
    Location:3 → 47
    ATP-synt_Eps; Mitochondrial ATP synthase epsilon chain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34539.1

Gene LinkOut

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Research Materials