mrpl-45 Large ribosomal subunit protein mL45 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mrpl-45
Official Full Name: Large ribosomal subunit protein mL45
Primary source: WormBase:WBGene00022493
Locus tag: CELE_Y119D3B.16
See related: AllianceGenome:WB:WBGene00022493
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human MRPL45 (mitochondrial ribosomal protein L45). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See mrpl-45 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 5

Sequence:: Chromosome: III; NC_003281.10 (1196389..1202008, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y119D3_450.b (e-PCR)
- UniSTS:323870

Y119D3_450.d (e-PCR)
- UniSTS:324572

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Large ribosomal subunit protein mL45

NP_497347.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

1196389..1202008 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064946.8 → NP_497347.3 Large ribosomal subunit protein mL45 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497347.3

Status: REVIEWED

UniProtKB/Swiss-Prot

Q95Y71

Conserved Domains (1) summary

smart00978
Location:156 → 304

Tim44; Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane