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nhr-277 Nuclear receptor [ Caenorhabditis elegans ]

Gene ID: 190799, updated on 9-Dec-2024

Summary

Official Symbol
nhr-277
Official Full Name
Nuclear receptor
Primary source
WormBase:WBGene00022374
Locus tag
CELE_Y94H6A.1
See related
AllianceGenome:WB:WBGene00022374
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hormone-mediated signaling pathway; regulation of transcription by RNA polymerase II; and tissue development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See nhr-277 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
10
Sequence:
Chromosome: IV; NC_003282.8 (2742994..2747485)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene BMERB domain-containing protein Neighboring gene Serpentine receptor class gamma

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nuclear receptor
NP_500250.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2742994..2747485
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067849.4NP_500250.2  Nuclear receptor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500250.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N2W3
    Conserved Domains (2) summary
    smart00399
    Location:70138
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    cl11397
    Location:260434
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators