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Y71H2AM.3 E3 ubiquitin-protein ligase E3D [ Caenorhabditis elegans ]

Gene ID: 190606, updated on 9-Dec-2024

Summary

Official Symbol
Y71H2AM.3
Official Full Name
E3 ubiquitin-protein ligase E3D
Primary source
WormBase:WBGene00022168
Locus tag
CELE_Y71H2AM.3
See related
AllianceGenome:WB:WBGene00022168
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cyclin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytosol and nucleus. Orthologous to human UBE3D (ubiquitin protein ligase E3D). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See Y71H2AM.3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (2805430..2811778)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Potassium channel domain-containing protein Neighboring gene Peptidase C1A papain C-terminal domain-containing protein Neighboring gene Elongation factor Tu, mitochondrial Neighboring gene Phosphatidylinositol-4,5-bisphosphate 4-phosphatase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cyclin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin conjugating enzyme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein autoubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein monoubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase E3D
NP_497622.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2805430..2811778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065221.3NP_497622.2  E3 ubiquitin-protein ligase E3D [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497622.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2AAC0
    Conserved Domains (1) summary
    cl19900
    Location:201467
    HECT_2; HECT-like Ubiquitin-conjugating enzyme (E2)-binding