U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ins-33 INSulin related [ Caenorhabditis elegans ]

Gene ID: 189313, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
ins-33
Official Full Name
INSulin related
Primary source
WormBase:WBGene00002116
Locus tag
CELE_W09C5.4
See related
AllianceGenome:WB:WBGene00002116
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in head muscle; head neurons; hypodermis; intestine; and tail. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ins-33 in Genome Data Viewer
Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003279.8 (13637845..13639311, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Serine/threonine-protein kinase dkf-1 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Insulin signaling promotes germline proliferation in C. elegans. Michaelson D, et al. Development, 2010 Feb. PMID 20110332, Free PMC Article
  2. Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest. Chen Y, et al. Dev Biol, 2014 Oct 15. PMID 25128585
  3. The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding. Hristova M, et al. Mol Cell Biol, 2005 Dec. PMID 16314527, Free PMC Article
  4. Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. Kwon JY, et al. Genomics, 2004 Apr. PMID 15028283
  5. Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans. Liu T, et al. BMC Dev Biol, 2004 Sep 20. PMID 15380030, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genetic analysis indicates that the developmental regulation of ins-33 mRNA involves the stage-specific repression of ins-33 transcription by LIN-14 via sequence-specific DNA binding.
    Title: The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
INSulin related
NP_493389.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    13637845..13639311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060988.4 → NP_493389.1  INSulin related [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493389.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U333
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools