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chil-27 GH18 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 188616, updated on 9-Dec-2024

Summary

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Official Symbol
chil-27
Official Full Name
GH18 domain-containing protein
Primary source
WormBase:WBGene00011848
Locus tag
CELE_T19H5.3
See related
AllianceGenome:WB:WBGene00011848
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See chil-27 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (9477867..9479696)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene GH18 domain-containing protein Neighboring gene GH18 domain-containing protein Neighboring gene ncRNA Neighboring gene Knot1 domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans. Gang SS, et al. PLoS Genet, 2022 Oct. PMID 36191002, Free PMC Article
  2. A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in Caenorhabditis elegans. Drury F, et al. Proc Natl Acad Sci U S A, 2023 Sep 26. PMID 37725647, Free PMC Article
  3. Chemosensory Neurons Modulate the Response to Oomycete Recognition in Caenorhabditis elegans. Fasseas MK, et al. Cell Rep, 2021 Jan 12. PMID 33440164, Free PMC Article
  4. Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans. Grover M, et al. PLoS Biol, 2024 Mar. PMID 38466732, Free PMC Article
  5. Natural Infection of C. elegans by an Oomycete Reveals a New Pathogen-Specific Immune Response. Osman GA, et al. Curr Biol, 2018 Feb 19. PMID 29398216

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GH18 domain-containing protein
NP_496035.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    9477867..9479696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063634.2 → NP_496035.1  GH18 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496035.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22597
    Conserved Domains (2) summary
    pfam00704
    Location:89 → 228
    Glyco_hydro_18; Glycosyl hydrolases family 18
    cl10447
    Location:97 → 235
    GH18_chitinase-like; The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have ...
Nucleotide Protein
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