lmtr-5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: lmtr-5
Official Full Name: Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5
Primary source: WormBase:WBGene00020101
Locus tag: CELE_R148.2
See related: AllianceGenome:WB:WBGene00020101
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to amino acid stimulus and positive regulation of TORC1 signaling. Predicted to be located in cytoplasm. Predicted to be part of Ragulator complex. Predicted to be active in lysosome. Orthologous to human LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to guanyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cellular response to amino acid stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cysteine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of TORC1 signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of Ragulator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Ragulator complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in lysosome	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosome	IEA Inferred from Electronic Annotation more info

Preferred Names: Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5

NP_497668.2

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