cnnm-5 Metal transporter cnnm-5 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cnnm-5
Official Full Name: Metal transporter cnnm-5
Primary source: WormBase:WBGene00011260
Locus tag: CELE_R13G10.4
See related: AllianceGenome:WB:WBGene00011260
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable transmembrane transporter activity. Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See cnnm-5 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 10

Sequence:: Chromosome: III; NC_003281.10 (3826255..3829205, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C36A4.10 (e-PCR)
- UniSTS:317957

R13G10.4 (e-PCR)
- UniSTS:306074

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in determination of adult lifespan	IEA Inferred from Electronic Annotation more info
involved_in determination of adult lifespan	IGI Inferred from Genetic Interaction more info	PubMed
involved_in magnesium ion homeostasis	IEA Inferred from Electronic Annotation more info
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of gonad development	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of gonad development	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Metal transporter cnnm-5

NP_497773.1

Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

3826255..3829205 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_065372.2 → NP_497773.1 Metal transporter cnnm-5 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497773.1

Status: REVIEWED

UniProtKB/Swiss-Prot

G5ED05

Conserved Domains (2) summary

pfam01595
Location:139 → 320

DUF21; Domain of unknown function DUF21

cl15354
Location:338 → 465

CBS_pair; The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called ...