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fpn-1.2 Solute carrier family 40 member [ Caenorhabditis elegans ]

Gene ID: 187727, updated on 4-Jan-2025

Summary

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Official Symbol
fpn-1.2
Official Full Name
Solute carrier family 40 member
Primary source
WormBase:WBGene00019977
Locus tag
CELE_R09B5.4
See related
AllianceGenome:WB:WBGene00019977
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable iron ion transmembrane transporter activity. Predicted to be involved in iron ion transmembrane transport. Predicted to be located in membrane. Is expressed in pharynx. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See fpn-1.2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (1462011..1464699, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glyco_18 domain-containing protein Neighboring gene 3-hydroxyacyl-CoA dehydrogenase Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene CTLH domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables iron ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in iron ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Solute carrier family 40 member
NP_503422.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1462011..1464699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071021.3 → NP_503422.2  Solute carrier family 40 member [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44607
    Conserved Domains (1) summary
    pfam06963
    Location:16 → 465
    FPN1; Ferroportin1 (FPN1)
Nucleotide Protein
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