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R02E12.4 Tektin [ Caenorhabditis elegans ]

Gene ID: 187525, updated on 4-Jan-2025

Summary

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Official Symbol
R02E12.4
Official Full Name
Tektin
Primary source
WormBase:WBGene00019828
Locus tag
CELE_R02E12.4
See related
AllianceGenome:WB:WBGene00019828
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in cilium assembly and cilium movement involved in cell motility. Predicted to be located in motile cilium. Predicted to be active in microtubule cytoskeleton. Is expressed in intestine and nervous system. Human ortholog(s) of this gene implicated in spermatogenic failure 81. Orthologous to several human genes including TEKT3 (tektin 3); TEKT4 (tektin 4); and TEKT5 (tektin 5). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See R02E12.4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (4005314..4007715)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Zgc: Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA Neighboring gene Heme transporter hrg-1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cilium movement involved in cell motility IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tektin
NP_001352248.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4005314..4007715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001365316.3 → NP_001352248.1  Tektin [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21641
    Conserved Domains (1) summary
    pfam03148
    Location:12 → 380
    Tektin; Tektin family
Nucleotide Protein
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