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K05F1.10 TIL domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 187030, updated on 9-Dec-2024

Summary

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Official Symbol
K05F1.10
Official Full Name
TIL domain-containing protein
Primary source
WormBase:WBGene00019411
Locus tag
CELE_K05F1.10
See related
AllianceGenome:WB:WBGene00019411
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Involved in innate immune response. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See K05F1.10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (5803675..5805473, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene Major sperm protein Neighboring gene protein of unknown function DX domain-containing protein Neighboring gene ncRNA Neighboring gene Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TIL domain-containing protein
NP_001343656.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5803675..5805473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356845.4 → NP_001343656.1  TIL domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21248
    Conserved Domains (1) summary
    pfam01826
    Location:53 → 115
    TIL; Trypsin Inhibitor like cysteine rich domain
Nucleotide Protein
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