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cpx-2 ComPleXin (synaptic protein) homolog [ Caenorhabditis elegans ]

Gene ID: 186917, updated on 4-Jan-2025

Summary

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Official Symbol
cpx-2
Official Full Name
ComPleXin (synaptic protein) homolog
Primary source
WormBase:WBGene00010520
Locus tag
CELE_K03A11.2
See related
AllianceGenome:WB:WBGene00010520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis and neurotransmitter transport. Is expressed in coelomocyte and neurons. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See cpx-2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
5
Sequence:
Chromosome: X; NC_003284.9 (13066974..13071220, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ShKT domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-28 Neighboring gene Sulfatase domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes. Courtney KC, et al. Nat Struct Mol Biol, 2022 Feb. PMID 35132256, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables syntaxin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
  
involved_in neurotransmitter transport IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ComPleXin (synaptic protein) homolog
NP_001379153.1
  • Product from WormBase gene class cpx;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13066974..13071220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392868.1 → NP_001379153.1  ComPleXin (synaptic protein) homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21168
    Conserved Domains (1) summary
    pfam05835
    Location:1 → 54
    Synaphin; Synaphin protein
Nucleotide Protein
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