U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pho-6 Lysosomal acid phosphatase [ Caenorhabditis elegans ]

Gene ID: 186114, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
pho-6
Official Full Name
Lysosomal acid phosphatase
Primary source
WormBase:WBGene00018696
Locus tag
CELE_F52E1.8
See related
AllianceGenome:WB:WBGene00018696
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphatase activity. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Orthologous to human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See pho-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (8392256..8394457, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Chondroitin proteoglycan 3 Neighboring gene pseudo Neighboring gene ZP domain-containing protein Neighboring gene SHSP domain-containing protein Neighboring gene Guanylate cyclase;Receptor-type guanylate cyclase gcy-7 Neighboring gene TPX2 domain-containing protein Neighboring gene Phosphatidylinositol-4,5-bisphosphate 4-phosphatase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Lysosomal acid phosphatase
NP_505167.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8392256..8394457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072766.4 → NP_505167.2  Lysosomal acid phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505167.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20662
    Conserved Domains (1) summary
    cl11399
    Location:19 → 314
    HP; Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous