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del-3 DEgenerin Like [ Caenorhabditis elegans ]

Gene ID: 184955, updated on 9-Dec-2024

Summary

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Official Symbol
del-3
Official Full Name
DEgenerin Like
Primary source
WormBase:WBGene00009144
Locus tag
CELE_F26A3.6
See related
AllianceGenome:WB:WBGene00009144
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in neurons. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See del-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (7670155..7672714, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein-tyrosine-phosphatase Neighboring gene DDE_Tnp_1_7 domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Golgin-84

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ASICs Mediate Food Responses in an Enteric Serotonergic Neuron that Controls Foraging Behaviors. Rhoades JL, et al. Cell, 2019 Jan 10. PMID 30580965, Free PMC Article
  2. High-fidelity encoding of mechanostimuli by tactile food-sensing neurons requires an ensemble of ion channels. Fok A, et al. Cell Rep, 2023 May 30. PMID 37119137, Free PMC Article
  3. A serotonergic circuit regulates aversive associative learning under mitochondrial stress in C. elegans. Chiang YC, et al. Proc Natl Acad Sci U S A, 2022 Mar 15. PMID 35254908, Free PMC Article
  4. Serotonin and dopamine modulate aging in response to food odor and availability. Miller HA, et al. Nat Commun, 2022 Jun 7. PMID 35672307, Free PMC Article
  5. Physiological insight into the conserved properties of Caenorhabditis elegans acid-sensing degenerin/epithelial sodium channels. Kaulich E, et al. J Physiol, 2023 May. PMID 36200489, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DEgenerin Like
NP_492135.1
  • Product from WormBase gene class del;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7670155..7672714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059734.4 → NP_492135.1  DEgenerin Like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492135.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93597
    Conserved Domains (1) summary
    pfam00858
    Location:17 → 226
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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