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nhr-178 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

Gene ID: 184560, updated on 9-Dec-2024

Summary

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Official Symbol
nhr-178
Official Full Name
Nuclear Hormone Receptor family
Primary source
WormBase:WBGene00017510
Locus tag
CELE_F16B4.9
See related
AllianceGenome:WB:WBGene00017510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including coelomocyte; intestine; neurons; pharynx; and spermatheca. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-178 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (1603906..1607953, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene F-box domain-containing protein Neighboring gene ncRNA Neighboring gene NR LBD domain-containing protein Neighboring gene Serpentine Receptor, class BC (Class B-like)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A metabolic regulatory network for the Caenorhabditis elegans intestine. Bhattacharya S, et al. iScience, 2022 Aug 19. PMID 35847555, Free PMC Article
  2. Nuclear hormone receptors in C. elegans. Antebi A. WormBook, 2006 Jan 3. PMID 18050471, Free PMC Article
  3. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear Hormone Receptor family
NP_503454.2
  • Product from WormBase gene class nhr;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1603906..1607953 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071053.4 → NP_503454.2  Nuclear Hormone Receptor family [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503454.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44635
    Conserved Domains (2) summary
    smart00399
    Location:23 → 95
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    pfam00104
    Location:193 → 397
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
Nucleotide Protein
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