U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nmgp-1 Neuronal Membrane GlycoProtein [ Caenorhabditis elegans ]

Gene ID: 184437, updated on 4-Jan-2025

Summary

Official Symbol
nmgp-1
Official Full Name
Neuronal Membrane GlycoProtein
Primary source
WormBase:WBGene00017437
Locus tag
CELE_F13H8.4
See related
AllianceGenome:WB:WBGene00017437
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in neuron projection development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cephalic sheath cell; neurons; somatic nervous system; tail ganglion; and ventral ganglion. Used to study depressive disorder. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Orthologous to human GPM6A (glycoprotein M6A); GPM6B (glycoprotein M6B); and PLP1 (proteolipid protein 1). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See nmgp-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (6260857..6262524)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Mitochondrial prohibitin complex protein 2 Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene Lipase_GDSL domain-containing protein Neighboring gene MSP domain-containing protein Neighboring gene Inosine/uridine-preferring nucleoside hydrolase domain-containing protein Neighboring gene SET domain-containing protein

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Neuronal Membrane GlycoProtein
NP_495253.2
  • Product from WormBase gene class nmgp;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    6260857..6262524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062852.7NP_495253.2  Neuronal Membrane GlycoProtein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495253.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19430
    Conserved Domains (1) summary
    cl02417
    Location:23193
    Myelin_PLP; Myelin proteolipid protein (PLP or lipophilin)