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pcrg-1 Parkin coregulated gene protein homolog [ Caenorhabditis elegans ]

Gene ID: 184039, updated on 4-Jan-2025

Summary

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Official Symbol
pcrg-1
Official Full Name
Parkin coregulated gene protein homolog
Primary source
WormBase:WBGene00017122
Locus tag
CELE_E04F6.2
See related
AllianceGenome:WB:WBGene00017122
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Is expressed in head neurons. Orthologous to human PACRG (parkin coregulated). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See pcrg-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (7200549..7201882)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MaoC-like domain-containing protein Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class D (Delta) Neighboring gene Serpentine Receptor, class D (delta)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modulation of inner junction proteins contributes to axoneme differentiation. Chen Z, et al. Proc Natl Acad Sci U S A, 2023 Jul 25. PMID 37463209, Free PMC Article
  2. The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis. Dawe HR, et al. J Cell Sci, 2005 Dec 1. PMID 16278296
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables Hsp70 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables Hsp90 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Parkin coregulated gene protein homolog
NP_495496.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7200549..7201882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063095.4 → NP_495496.2  Parkin coregulated gene protein homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495496.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19060
    Conserved Domains (1) summary
    pfam10274
    Location:102 → 290
    ParcG; Parkin co-regulated protein
Nucleotide Protein
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