U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

atg-10 Ubiquitin-like-conjugating enzyme ATG10 [ Caenorhabditis elegans ]

Gene ID: 183959, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
atg-10
Official Full Name
Ubiquitin-like-conjugating enzyme ATG10
Primary source
WormBase:WBGene00008427
Locus tag
CELE_D2085.2
See related
AllianceGenome:WB:WBGene00008427
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin-like protein transferase activity. Involved in autophagy. Predicted to be active in phagophore assembly site. Orthologous to human ATG10 (autophagy related 10). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See atg-10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (8659135..8659800)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Integrase Neighboring gene Glutamine-dependent carbamoyl-phosphate synthase Neighboring gene Translation initiation factor eIF2B subunit epsilon Neighboring gene PIGA GPI anchor biosynthesis domain-containing protein Neighboring gene E3 ubiquitin-protein ligase etc-1 Neighboring gene Ral GTPase-activating protein subunit alpha/beta N-terminal domain-containing protein;Rap-GAP domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Autophagy in C. elegans. Meléndez A, et al. WormBook, 2009 Aug 24. PMID 19705512
  2. Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans. Doering KRS, et al. Elife, 2022 Mar 14. PMID 35285794, Free PMC Article
  3. Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans. Khan LA, et al. Biochem Biophys Res Commun, 2008 Apr 11. PMID 18261464
  4. Autophagy during ageing - from Dr Jekyll to Mr Hyde. Wilhelm T, et al. FEBS J, 2018 Jul. PMID 29630766
  5. Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans. Lin H, et al. Front Aging Neurosci, 2022. PMID 35645788, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-like protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in autophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in glycophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in phagophore assembly site IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Ubiquitin-like-conjugating enzyme ATG10
NP_495839.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8659135..8659800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063438.3 → NP_495839.2  Ubiquitin-like-conjugating enzyme ATG10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495839.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18991
    Conserved Domains (1) summary
    pfam03987
    Location:54 → 122
    Autophagy_act_C; Autophagocytosis associated protein, active-site domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools