U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

him-5 High Incidence of Males (increased X chromosome loss) [ Caenorhabditis elegans ]

Gene ID: 183932, updated on 23-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
him-5
Official Full Name
High Incidence of Males (increased X chromosome loss)
Primary source
WormBase:WBGene00001864
Locus tag
CELE_D1086.4
See related
AllianceGenome:WB:WBGene00001864
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination and meiotic chromosome segregation. Located in condensed chromosome. Is expressed in gonad. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See him-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (14090426..14092454)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene DUF19 domain-containing protein Neighboring gene ncRNA Neighboring gene DUF19 domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Vesicle fusion, pseudopod extension and amoeboid motility are induced in nematode spermatids by the ionophore monensin. Nelson GA, et al. Cell, 1980 Feb. PMID 7357613
  2. Relationship between plasma membrane mobility and substrate attachment in the crawling movement of spermatozoa from Caenorhabditis elegans. Pavalko FM, et al. Cell Motil Cytoskeleton, 1988. PMID 3208296
  3. Posttranslational insertion of a membrane protein on Caenorhabditis elegans sperm occurs without de novo protein synthesis. Pavalko FM, et al. J Cell Biochem, 1989 Oct. PMID 2613747
  4. Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans. Meneely PM, et al. Genetics, 2012 Apr. PMID 22267496, Free PMC Article
  5. Whole-animal connectomes of both Caenorhabditis elegans sexes. Cook SJ, et al. Nature, 2019 Jul. PMID 31270481, Free PMC Article

See all (138) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. rec-1; him-5 double mutants are synthetic-lethal due to a defect in meiotic double-strand break formation
    Title: REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans.
  2. him-5 is suppressed by changes in X chromosome architecture.
    Title: Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in meiotic chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in condensed chromosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
High Incidence of Males (increased X chromosome loss)
NP_001256555.1
  • Product from WormBase gene class him;
    Confirmed by transcript evidence
NP_001256556.1
  • Product from WormBase gene class him;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14090426..14092454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269626.2 → NP_001256555.1  High Incidence of Males (increased X chromosome loss) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256555.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17724

  2. NM_001269627.3 → NP_001256556.1  High Incidence of Males (increased X chromosome loss) [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256556.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1B6V2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools