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del-7 Acid-sensing ion channel 1-like [ Caenorhabditis elegans ]

Gene ID: 183498, updated on 9-Dec-2024

Summary

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Official Symbol
del-7
Official Full Name
Acid-sensing ion channel 1-like
Primary source
WormBase:WBGene00016699
Locus tag
CELE_C46A5.2
See related
AllianceGenome:WB:WBGene00016699
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in NSML and NSMR. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See del-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (7760417..7762856)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Peroxidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Double-Strand Break factor Neighboring gene Uncharacterized protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ASICs Mediate Food Responses in an Enteric Serotonergic Neuron that Controls Foraging Behaviors. Rhoades JL, et al. Cell, 2019 Jan 10. PMID 30580965, Free PMC Article
  2. A genetically encoded tool for reconstituting synthetic modulatory neurotransmission and reconnect neural circuits in vivo. Hawk JD, et al. Nat Commun, 2021 Aug 9. PMID 34373460, Free PMC Article
  3. A serotonergic circuit regulates aversive associative learning under mitochondrial stress in C. elegans. Chiang YC, et al. Proc Natl Acad Sci U S A, 2022 Mar 15. PMID 35254908, Free PMC Article
  4. Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale. Dag U, et al. Cell, 2023 Jun 8. PMID 37192620, Free PMC Article
  5. Serotonin and dopamine modulate aging in response to food odor and availability. Miller HA, et al. Nat Commun, 2022 Jun 7. PMID 35672307, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Acid-sensing ion channel 1-like
NP_501276.4
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7760417..7762856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068875.5 → NP_501276.4  Acid-sensing ion channel 1-like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501276.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18651
    Conserved Domains (1) summary
    cl02990
    Location:434 → 473
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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