sgo-1 Shugoshin [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: sgo-1
Official Full Name: Shugoshin
Primary source: WormBase:WBGene00016381
Locus tag: CELE_C33H5.15
See related: AllianceGenome:WB:WBGene00016381
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in cell division and chromosome segregation. Predicted to be located in chromosome, centromeric region and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sgo-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 8

Sequence:: Chromosome: IV; NC_003282.8 (7794857..7796482, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia.
Title: The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia.
The authors propose that SGO-1 acts during pre-meiotic replication to ensure fully functional meiotic chromosome architecture, rendering these chromosomes competent for checkpoint activity and normal progression of meiotic recombination.
Title: Shugoshin Is Essential for Meiotic Prophase Checkpoints in C. elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C33H5.15 (e-PCR)
- UniSTS:308704

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in cell cycle	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in chromosome segregation	IEA Inferred from Electronic Annotation more info
involved_in organelle organization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info
located_in chromosome, centromeric region	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Shugoshin

NP_001294168.1

Confirmed by transcript evidence

NP_501290.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

7794857..7796482 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001307239.2 → NP_001294168.1 Shugoshin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001294168.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18412, W6SBE3

Conserved Domains (1) summary

pfam07558
Location:28 → 71

Shugoshin_N; Shugoshin N-terminal coiled-coil region
NM_068889.5 → NP_501290.2 Shugoshin [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501290.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q18412

Conserved Domains (1) summary

pfam07558
Location:28 → 71

Shugoshin_N; Shugoshin N-terminal coiled-coil region