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irg-6 CUB-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183126, updated on 9-Dec-2024

Summary

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Official Symbol
irg-6
Official Full Name
CUB-like domain-containing protein
Primary source
WormBase:WBGene00007864
Locus tag
CELE_C32H11.1
See related
AllianceGenome:WB:WBGene00007864
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in response to gamma radiation. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See irg-6 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
9
Sequence:
Chromosome: IV; NC_003282.8 (12912722..12914969, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CUB domain-containing protein Neighboring gene CUB-like domain-containing protein Neighboring gene Serpentine Receptor, class Z Neighboring gene CUB-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The DNA damage-inducible C. elegans tankyrase is a nuclear protein closely linked to chromosomes. White C, et al. Mol Cell Biochem, 2009 Apr. PMID 19104912
  2. Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection. Pukkila-Worley R, et al. PLoS Genet, 2012. PMID 22719261, Free PMC Article
  3. bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans. Estes KA, et al. Proc Natl Acad Sci U S A, 2010 Feb 2. PMID 20133860, Free PMC Article
  4. The mechanoreceptor DEG-1 regulates cold tolerance in Caenorhabditis elegans. Takagaki N, et al. EMBO Rep, 2020 Mar 4. PMID 32009302, Free PMC Article
  5. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Troemel ER, et al. PLoS Genet, 2006 Nov 10. PMID 17096597, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in response to gamma radiation IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
CUB-like domain-containing protein
NP_001255687.1
  • Confirmed by transcript evidence
NP_001255688.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12912722..12914969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268758.2 → NP_001255687.1  CUB-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255687.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9G327
    Conserved Domains (1) summary
    pfam02408
    Location:18 → 135
    CUB_2; CUB-like domain

  2. NM_001268759.3 → NP_001255688.1  CUB-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255688.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9G326
    Conserved Domains (1) summary
    pfam02408
    Location:18 → 135
    CUB_2; CUB-like domain
Nucleotide Protein
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